Setting the blocks on the diagonal is something that mid-19th-century quilters liked to do. It presents a few design challenges,which readers have solved in a variety of ways. What to do with the edge triangles? Above, a nice solution from Conny's Quilts.
Putting the blocks on point means you don't need as many---you can make two quilts, especially if you alternate with unpieced squares.
And if you put a large block in the center--- a feathered star is always eyecatching--- you need fewer than 52.
Leigh Ann used a Southern Star block for the center.
And then you can do this--- but I'm not going to figure out the math.
Lois has the border on it now. See her stream for a detailed picture of the clever double geese design. She says it's paper pieced. http://www.flickr.com/photos/l_olsen/